ライフサイエンス 新着論文レビュー

First author's

Src/c-Abl経路は筋萎縮性側索硬化症の潜在的な治療の標的である

2017年6月16日

今村恵子・井上治久
(京都大学iPS細胞研究所 増殖分化機構研究部門)
email:井上治久
DOI: 10.7875/first.author.2017.056

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Keiko Imamura , Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta, Takayuki Kondo, Shiho Kitaoka, Akira Ohta, Akito Tanaka, Dai Watanabe, Mitsuya Morita, Hiroshi Takuma, Akira Tamaoka, Tilo Kunath, Selina Wray, Hirokazu Furuya, Takumi Era, Kouki Makioka, Koichi Okamoto, Takao Fujisawa, Hideki Nishitoh, Kengo Homma, Hidenori Ichijo, Jean-Pierre Julien, Nanako Obata, Masato Hosokawa, Haruhiko Akiyama, Satoshi Kaneko, Takashi Ayaki, Hidefumi Ito, Ryuji Kaji, Ryosuke Takahashi, Shinya Yamanaka, Haruhisa Inoue
Science Translational Medicine, 9, eaaf3962 (2017)

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筋萎縮性側索硬化症の発症にかかわるアネキシンA11の変異

2017年6月7日

柴田秀樹・牧 正敏
(名古屋大学大学院生命農学研究科 応用分子生命科学専攻分子細胞制御学研究分野)
email:柴田秀樹
DOI: 10.7875/first.author.2017.049

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.
Bradley N. Smith, Simon D. Topp, Claudia Fallini, Hideki Shibata, Han-Jou Chen, Claire Troakes, Andrew King, Nicola Ticozzi, Kevin P. Kenna, Athina Soragia-Gkazi, Jack W. Miller, Akane Sato, Diana Marques Dias, Maryangel Jeon, Caroline Vance, Chun Hao Wong, Martina de Majo, Wejdan Kattuah, Jacqueline C. Mitchell, Emma L. Scotter, Nicholas W. Parkin, Peter C. Sapp, Matthew Nolan, Peter J. Nestor, Michael Simpson, Michael Weale, Monkel Lek, Frank Baas, J. M. Vianney de Jong, Anneloor L. M. A. ten Asbroek, Alberto Garcia Redondo, Jesús Esteban-Pérez, Cinzia Tiloca, Federico Verde, Stefano Duga, Nigel Leigh, Hardev Pall, Karen E. Morrison, Ammar Al-Chalabi, Pamela J. Shaw, Janine Kirby, Martin R. Turner, Kevin Talbot, Orla Hardiman, Jonathan D. Glass, Jacqueline De Belleroche, Masatoshi Maki, Stephen E. Moss, Christopher Miller, Cinzia Gellera, Antonia Ratti, Safa Al-Sarraj, Robert H. Brown Jr., Vincenzo Silani, John E. Landers, Christopher E. Shaw
Science Translational Medicine, 9, eaad9157 (2017)

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抗炎症タンパク質Del-1はサルにおいて炎症性の骨吸収を抑制する

2015年10月29日

前川 知樹
(米国Pennsylvania大学School of Dental Medicine,Department of Microbiology)
email:前川知樹
DOI: 10.7875/first.author.2015.123

DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates.
Jieun Shin, Tomoki Maekawa, Toshiharu Abe, Evlambia Hajishengallis, Kavita Hosur, Kalyani Pyaram, Ioannis Mitroulis, Triantafyllos Chavakis, George Hajishengallis
Science Translational Medicine, 7, 307ra155 (2015)

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